Research Direction:
By using the physical characteristics of multi-spectrum and different spectral bands, the macroscopic and microstructure properties of biomedicine were explored, and through all-around research on cells and tissues, the application of precision spectral biomedicine detection technology in biological detection and biomedicine was promoted. The precision spectrum biomedical detector and the analytical instrument used for biomedical assisted diagnosis is developed. The multi-spectral fingerprint information of biological tissues is formed by exploring the multi-spectral signal characteristic spectrum of different biological structures and influencing factors in vivo and vitro. A real-time multi-spectral spectral analysis system is realized by constructing multi-band spectral analysis suitable for the detection of biological tissues or structures, providing supports for medical diagnosis.
From micro and macro perspectives, through all-around research on the cell, tissue, organ and individual, with the practical precision spectrum biomedical detection system as the mainline, to satisfy the demands of national biomedical development. By solving the core problem of interaction between living organisms and electromagnetic field, such as high efficient broadband terahertz radiation source, low loss terahertz devices, integrated stabilization system, etc., and by applying the core devices in the application system, the research can reach the detection of biological cells, tissues and integrated spectrum system.
The research direction of the team is to use the physical characteristics of multi-spectrum and its different spectral bands to detect the macro and microstructure properties in biomedicine and promote the application of precision spectrum biomedical detecting technology in biological detection and biomedicine through all-round research of cells and tissues, At the same time, the team also emphasizes the R&D of precision spectrum biomedical detecting and analysis instruments and equipment for biomedical auxiliary diagnosis. After exploring the characteristic spectrum of multispectral signals with different biological structures and the impact factors in vivo and in vitro, there forms the multispectral fingerprint information of biological tissues After constructing multi-band spectral analysis suitable for biological tissue or structure detection, a real-time multiband spectral analysis system can be realized to provide auxiliary support for future medical diagnosis.
Infrastructure:
The team has sets of femtosecond laser systems and Fourier transform infrared spectrometer, terahertz emission source, terahertz detector, high-speed oscilloscope, terahertz time-domain spectrometer and other instruments.
Principle Investigator: Hu Qing, USST, School of Optical Electrical and Computer Engineering, Professor (doctoral supervisor), distinguished professor of “National-A-Thousand” Program, distinguished professor of “Changjiang Scholar”, fellow of American Physical Society (APS), fellow of Optical Society of America (OSA), fellow of Institute of Electrical and Electronics Engineers (IEEE) and fellow of American Association for the Advancement of Science (AAAS).
In total, more than 200 SCI papers were published. Papers were cited more than 6,564 times, and the h-index reached 45. Several papers were published in top international journals such as Nature Photonics, Nature Physics and Nature Communications. Winner of the Technology Transfer Award of the Lawrence Berkeley Laboratory, William Streifer Scientific Achievement Award of the IEEE, WOFE-07 Best Paper Award (of Frontier Electronic Products Seminar), and the Nick Holonyak, Jr. Award and Kenneth J Button Prize. Professor Hu Qing was employed in 2014 as "Hujiang" Distinguished Professor of USST, the two sides collaboratively study spectrum imaging using high power quantum-cascade lasers as the radiation sources. By applying a near-field scanning optical microscopy measurement scheme, the first set of domestic spectrum microscopic imaging systems was established, with a spatial resolution higher than 100 nm, and multi-spectral detection research on biological material, such as proteins, DNA, was carried out.
Based on the major technological breakthroughs made in the cooperative research, together with the Chinese Academy of Sciences and other institutions, USST has received approval of the Key Scientific Instruments and Equipment Development Project "Spectral Microscopic Imaging Detector" of 2017 National Key R&D Plan. Professor Hu Qing is a key researcher of the project. In addition, Professor Hu also guided the research work of young teachers in the THz research team of USST and made many research achievements.
Honors (Achievements):
·Titles of Professor Peng Yan:
·Shanghai “May 4th Youth Medal”, 2017
·Shanghai “Pacesetters of Women Rendering Meritorious Service”, 2017
·Shanghai “Outstanding Young Scholars”, 2017
·Shanghai “Shuguang Scholars”, 2017
·Shanghai “Qimingxing Talents”, 2017
·Shanghai “Hujiang Talents Program”, 2016
·Shanghai “Chenguang Scholars”, 2016
Contacts: Room 305, new Opto-electronic Building USST, No.516 Jungong Road, Yangpu District, Shanghai 200093.